In the present era, with the rapid expansion of empirical sciences and the emergence of fundamental questions about the origin, structure, and future of the universe, the need to revisit and re-examine religious texts in light of these achievements is felt more than ever. This study aims to conduct a comparative analysis of the cosmological verses of the Holy Quran and the latest findings in modern physics, astronomy, and cosmology, in order to analyze the convergence and interaction between revelation and empirical science. The research employs an analytical-comparative and interdisciplinary approach, examining the cosmic concepts and themes of the Quran alongside established scientific theories. The findings indicate that many Quranic verses, despite their revelation in a different cultural and scientific context, possess profound semantic capacities that align with fundamental discoveries in modern cosmology. This alignment does not imply the provision of scientific details but rather represents a rhetorical correspondence and the potential for a deeper understanding of the Quran’s general concepts across different scientific eras. Furthermore, the examined verses can provide a basis for reflection on the order, grandeur, and dynamism of creation, contributing to the deepening of philosophical understanding, the enrichment of scientific and religious discussions, and the facilitation of interaction between religious and scientific knowledge. Therefore, a comparative study and synergy between science and revelation can offer a more comprehensive and integrated understanding of the universe and the truth of existence, opening new pathways for the connection between religious and scientific knowledge, which underscores the importance of interdisciplinary approaches in contemporary research.